Scientifique en biologie cellulaire h/f

La plateforme Biogenovac de CEVA Santé Animale est dédiée à l'exploitation des technologies génomiques pour développer des solutions thérapeutiques innovantes, notamment dans les domaines de l'immunologie et de la vaccination.
Dans ce contexte, nous recherchons un(e) scientifique en biologie cellulaire pour rejoindre notre équipe et piloter la mise en place et le fonctionnement du laboratoire de culture cellulaire de la plateforme, avec un focus particulier sur les modèles chiens/chats.

* Mettre en place et gérer le laboratoire de culture cellulaire : installation des équipements, organisation des flux de travail, respect des normes de biosécurité et de qualité.
* Développer et caractériser des modèles cellulaires spécifiques aux espèces canines et félines, en lien avec les besoins des projets thérapeutiques.
* Réaliser des expériences de transfection cellulaire (acides nucléiques au sens large) pour étudier l'expression génique et protéique.
* Évaluer in vitro des constructions génomiques afin d'en analyser la fonctionnalité et l'expression protéique dans les modèles cellulaires pertinents.
* Utiliser des techniques telles que Western blot, ELISA, immunofluorescence pour quantifier et valider l'expression des protéines.
Mettre en oeuvre des tests fonctionnels pour évaluer la réponse pro-inflammatoire, incluant la quantification de cytokines et l'utilisation de systèmes rapporteurs (ex. : luciférase, GFP).
* Collaborer étroitement avec les équipes de génomique et de bioinformatique de la plateforme, ainsi qu'en transversal avec les équipes projets en charge des produits biotechnologiques.
* Contribuer à la conception expérimentale, au développement de protocoles, à l'analyse des données et à la rédaction de rapports techniques. Cell Biology Scientist M/F

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Together, let's share our talents.

As a global leader in animal health, Ceva Animal Health believes our success is linked to our passionate people researching, developing, producing and supplying innovative health solutions for all animals, which contributes to the future of our diverse planet.

We are committed to ensuring the highest possible level of care and well-being for farm animals (poultry, pigs, ruminants), companion animals (dogs and cats) and wildlife.

Indeed, Our Together, Beyond Animal Health vision emphasizes that the health and wellbeing of people, animals and our planet are totally interlinked. More than ever, Ceva is committed to a "One Health" approach.

As part of our Diversity, Equity and Inclusion policy, Ceva Animal Heath is committed to the employment of people with disabilities and will make reasonable accommodations throughout the interview process to ensure an inclusive and accessible experience for all applicants. To request an accommodation, please contact a member of the Ceva Talent Acquisition team.

missions :

The Biogenovac platform at
CEVA Santé Animale is dedicated to leveraging genomic technologies to develop
innovative therapeutic solutions, particularly in the fields of immunology, vaccination, and inflammation modulation. In
this context, We are seeking a Cell Biology Scientist to join
our team and lead the setup and operation of the cell culture
laboratory within the platform with a specific focus for companion
animals (dogs and cats).

Key Responsibilities :

* Set
up and manage the cell culture laboratory, including equipment installation,
workflow organization, and compliance with biosafety and quality
standards.

* Develop
and characterize species-specific cellular models (canine
and feline) aligned with therapeutic project needs.

* Perform cell
transfection experiments with different nucleic acids to study gene and protein expression.

* Evaluate
genomic constructs in vitro to assess theirb functionality and protein
expression in relevant cellular models.

* Use
techniques such as Western blot, ELISA, immunofluorescence, to
quantify and validate protein expression.

* Implement
functional assays to
assess pro-inflammatory responses, including cytokine
quantification and reporter systems (e.g., luciferase,
GFP, SEAP).

* Collaborate
closely with genomics and bioinformatics teams within the platform.
Collaborate in transverse with projects team in charge of biotech projects.

* Contribute
to experimental design, protocol development, data analysis, and technical
reporting.

Your
profile :

* Master's degree (MSc) in Cell Biology,
Biotechnology, or a related field.
* Proven professional experience (beyond internships) in a
pharmaceutical, biotech, or academic setting involving cell biology.
* Strong hands-on experience in
cell culture, transfection, and protein expression analysis.
* Experience in evaluating genomic
constructs and their biological activity is
highly valued.
* Knowledge of immunology,
inflammation, or applied genomics is a plus.
* Demonstrated ability to work
independently,
manage lab operations, and proactively solve technical challenges.
* A strong asset (optional) : expertise in nucleic
acid delivery systems such as lipid nanoparticles (LNPs), polymers,
or non-viral carriers.
* Proficiency in data analysis
tools (Excel, GraphPad Prism, etc.).
* Scientific English (reading and
writing) required.