Preclinical pharmacology expert- f - m- cdi h/f

Qui sommes-nous ?

Pierre Fabre est le 2ème laboratoire dermo-cosmétique mondial, le 2ème groupe pharmaceutique privé français et le leader des produits vendus hors prescription dans les pharmacies en France. Son portefeuille compte plusieurs franchises médicales et marques internationales dont Pierre Fabre Oncologie, Pierre Fabre Dermatologie, Eau Thermale Avène, Klorane, Ducray, René Furterer, A-Derma, Naturactive et Pierre Fabre Oral Care.

Implanté depuis toujours en région Occitanie, fabricant plus de 95% de ses produits en France, le groupe emploie près de 10 000 collaborateurs dans le monde et distribue ses produits dans quelque 130 pays. Pierre Fabre est détenu à 86% par la Fondation Pierre Fabre, une fondation reconnue d'utilité publique, et secondairement par ses collaborateurs à travers un plan d'actionnariat salarié.

En 2021, Ecocert Environnement a évalué la démarche de responsabilité sociétale et environnementale du Groupe selon la norme ISO 26000 du développement durable et lui a attribué le niveau « Excellence ».

Pierre Fabre est reconnu comme l'un des « Meilleurs Employeurs du Monde 2021 » par Forbes. Notre groupe est classé dans le Top 6 de l'industrie cosmétique et dans le Top 7 de l'industrie pharmaceutique dans le monde. Nous sommes convaincus que notre engagement et notre passion font préserver notre indépendance et vivre notre raison d'être.

Votre mission

Pierre Fabre Group is committed to Medical Care R&D to bring novel, innovative therapeutic opportunities to patients in need. Oncology is a major priority and constitutes a strategic focus for the Pierre Fabre Group.

The internal R&D pipeline, supplemented with future external opportunities, will BE central in shaping the future orientation of Pierre Fabre Medical Care.

We are seeking a talented, highly motivated and experienced Preclinical Pharmacology Expert to join our growing oncology drug discovery group in Toulouse.

The ideal candidate will have extensive experience in pre-clinical in vivo pharmacology and will contribute, with both internal and external partners to define and oversee outsourced in vivo studies. This is an exciting opportunity to directly contribute to drug candidate selection and characterization across different projects.

Key skills and responsibilities
- In depth expertise in in vivo pharmacology : PK/PD/efficacy relationship analyses, biomarker studies, knowledge of relevant mechanistic and disease models to support drug discovery and translational research
- Ability to propose and assess new methodologies and technologies for in vivo (and possibly in vitro) pharmacology evaluation Work internally with Core Team members including drug discovery/PK/toxicology and biomarker team members to establish the in vivo evaluation plan for the research projects
- Identify CROs of choice and coordinate outsourcing of in vivo studies and subsequent investigations as needed
- Oversee study design, analysis and interpretation of in vivo pharmacology studies within the defined timelines
- Thorough understanding of the different therapeutic modalities (small molecules, antibodies including Antibody-Drug-Conjugates) and their specificity related to in vivo pharmacology
- Knowledge of the regulatory and ethical framework related to in vivo activities
- Proficiency in both written and spoken English, with strong presentation and communication skills
- Experience working in a cross-functional and dynamic environment
- Self-motivated and collaborative with ability to work on multiple projects with multi-disciplinary teams and external partners

This position is compatible with teleworking up to 2 days a week after the trial period.

We offer an attractive remuneration/benefits package : Incentives, profit-sharing, Pierre Fabre shareholding with matching contribution, health and provident insurance, 16 days of holidays (RTT) in addition to 25 days of personal holidays, public transport participation, very attractive CE

Qui êtes-vous ?

Profile
- Master's degree or PhD in a relevant scientific discipline (e.g., pharmacology, biology) with strong expertise in oncology.
- At least 10 years of experience as in vivo pharmacologist in a pharmaceutical or biotech company.
- Habilitation (Level 1) is required to conduct these animal studies

Nous sommes convaincus que la diversité est une source d'épanouissement, d'équilibre social et de complémentarité pour nos collaborateurs, nos offres sont donc ouvertes à toutes et tous sans restriction.