Pk pd project manager- senior pharmacokinetics pharmacodynamics scientist m - f - cdi h/f

Qui sommes-nous ?

Pierre Fabre est le 2ème laboratoire dermo-cosmétique mondial, le 2ème groupe pharmaceutique privé français et le leader des produits vendus hors prescription dans les pharmacies en France. Son portefeuille compte plusieurs franchises médicales et marques internationales dont Pierre Fabre Oncologie, Pierre Fabre Dermatologie, Eau Thermale Avène, Klorane, Ducray, René Furterer, A-Derma, Naturactive et Pierre Fabre Oral Care.

Implanté depuis toujours en région Occitanie, fabricant plus de 95% de ses produits en France, le groupe emploie près de 10 000 collaborateurs dans le monde et distribue ses produits dans quelque 130 pays. Pierre Fabre est détenu à 86% par la Fondation Pierre Fabre, une fondation reconnue d'utilité publique, et secondairement par ses collaborateurs à travers un plan d'actionnariat salarié.

En 2021, Ecocert Environnement a évalué la démarche de responsabilité sociétale et environnementale du Groupe selon la norme ISO 26000 du développement durable et lui a attribué le niveau « Excellence ».

Pierre Fabre est reconnu comme l'un des « Meilleurs Employeurs du Monde 2021 » par Forbes. Notre groupe est classé dans le Top 6 de l'industrie cosmétique et dans le Top 7 de l'industrie pharmaceutique dans le monde. Nous sommes convaincus que notre engagement et notre passion font préserver notre indépendance et vivre notre raison d'être.

Votre mission

We're looking for a talented and driven PKPD project leader with a strong background in drug development and a passion for innovation to join our dynamic PKPD department. If you thrive in international, cross-functional environments and want to shape the future of therapeutic discovery, we want to hear from you.

As a key scientific leader and member of the core project teams, you will design and implement cutting-edge PKPD, DMPK, and ADME strategies from early discovery through preclinical development. You'll BE the face of the PKPD department in internal and external engagements-collaborating with global experts, regulatory authorities, and strategic partners.

What You'll Do
- Strategic Leadership : Define PKPD needs across all development stages-from early preclinical to First-in-Human-ensuring alignment on study design, timelines, and budgets.
- Study Oversight : Lead or coordinate in vitro, in vivo, and in silico PK/PKPD studies, whether conducted in-house or outsourced, ensuring scientific rigor and operational excellence.
- Asset Evaluation : Provide expert PKPD assessments of external assets, contributing to strategic decision-making in licensing or acquisition.
- Cross-Functional Collaboration : Work closely with clinicians, statisticians, pharmacologists, toxicologists, and regulatory experts to drive project success.
- Scientific Documentation : Author key sections of regulatory and scientific documents, including study protocols, Investigator's Brochures (IB), IND/IMPDs, NDAs, PIPs, and Risk Management Plans.
- Global Engagement : Represent the PKPD function in interactions with regulatory bodies, CROs, key opinion leaders, and business partners.

What You Bring
- Proven experience in PKPD within drug development, ideally in an international setting.
- Strong scientific acumen and ability to translate complex data into actionable insights.
- Excellent communication skills and a collaborative mindset.

This position is compatible with teleworking up to 2 days a week after the trial period.

We offer an attractive remuneration/benefits package : Incentives, profit-sharing, Pierre Fabre shareholding with matching contribution, health and provident insurance, 16 days of holidays (RTT) in addition to 25 days of personal holidays, public transport participation, very attractive CE

Qui êtes-vous ?
- At least 5 year industry experience in a multicultural English speaking environment, with a solid track record in PK/PKPD drug development
- Practical knowledge and experience of PK/PKPD preclinical and clinical trial design and execution, including data collection, analysis and reporting approaches + filling of regulatory dossiers.
- Previous experience (hands-on) interpretation of PK and PKPD data, with in-silico methods.
- Significant track record with early drug development phases or moving candidate drugs to the clinic.
- Fluency in English, both written and spoken.

Nous sommes convaincus que la diversité est une source d'épanouissement, d'équilibre social et de complémentarité pour nos collaborateurs, nos offres sont donc ouvertes à toutes et tous sans restriction.