Sr principal scientist, immune tolerance and autoimmunity

_Le contenu du poste est libellé en anglais car il nécessite de nombreuses interactions avec nos filiales à l'international, l'anglais étant la langue de travail._ _This job offer is accessible to all, regardless of gender._ Job title : _Sr Principal scientist, Immune tolerance and autoimmunity_ _Location: Vitry-Sur-Seine_ _Grade: L3_ _Hiring Manager: Rami LISSILAA_ _About the job_ As Sr Principal scientist within our Immune tolerance and autoimmunity cluster, you'll develop innovative therapeutic approaches and identify novel targets in autoimmunity, leveraging your expertise to design groundbreaking preclinical studies, mentor team members, and collaborate across functions to advance transformative science for patients. Ready to get started? Sanofi's Immunology and Inflammation Research is establishing an Immune Regulation and Autoimmune Diseases center of excellence at Vitry, seeking a Sr Principal Scientist with immunology expertise. You'll contribute to drug discovery and lead research within the immune tolerance cluster, focusing on identifying novel therapeutic concepts that could transform autoimmune disease treatment. The team will target pathogenic immune pathways, explore disruptive modalities, and develop translational assays for screening therapeutic candidates. Looking for an environment that values enthusiasm, collaboration, and innovation for patients? Join us to transform Immunology research into real-world solutions. About Sanofi: We're an R&D-driven, AI-powered biopharma company committed to improving people's lives and delivering compelling growth. Our deep understanding of the immune system - and innovative pipeline - enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people's lives. Main responsibilities: Lead innovative projects and research activities to develop differentiated and high value projects and manage research programs in the emerging area of immune tolerance, immune regulation and autoimmunity Advance cutting-edge science to enable continual innovation through the identification of new targets and disruptive therapeutic approaches in the field of Immune tolerance and autoimmunity Apply scientific expertise and judgement to initiate, design, direct and execute preclinical study experiments and/or studies in support of research project goals in a time sensitive manner Act as an impactful contributor and leader of project teams and transverse and cross-functional initiatives Work across R&D organization to test and advance innovative projects, hypotheses and methodologies: encourages curiosity and challenges the status quo in order to foster innovation Mentor, motivate and train a laboratory team, including Sr technicians, scientists and eventually PhD student and post-docs Provide strong scientific and technical leadership in the design and execution of a broad range of complex immune tolerance assays to elucidate mechanism of action and understand disease biology Participate to the evaluation of preclinical/clinical-stage in-licencing and collaboration opportunities Create and maintain a work environment in which scientific excellence and innovation in immunology are fostered _About you_ Experience: Leading-edge knowledge of Immunology including T/B cell biology or innate immunity and relevant experience in the immunology/inflammation related disease areas Demonstrated ability to identify new targets using genetic, transcriptomics or other bioinformatics analysis is desirable Hands-on manager of people at different levels including technicians, PhD, scientists Track record of developing efficient discovery processes and leading complex cross-functional team collaborations, including managing relationships with internal and external collaborators Soft and technical skills : Excellent interpersonal and communication skills: impactful oral and written communication Strong scientific curiosity and rigor, excellent interpersonal, technical and analytic skills, high ethical standards Fast learner, flexibility to rapidly change priorities and deadlines and ability to lead others through change in a dynamic, fast paced industry and work environment Education : PhD level in Immunology, with a relevant academic research (post doc) and/or industrial experience Languages : English, (French desirable) _Why choose us?_ Work at the forefront of drug discovery, harnessing cutting-edge AI, data, and digital platforms to push the boundaries of science Help improve the lives of millions of people globally by making drug development quicker and more effective Enjoy opportunities to collaborate beyond your area of expertise, working with diverse teams across science, clinical, and digital fields to spark new ideas and drive breakthroughs Join a workplace where diversity, equity, and inclusion are at the core, with Employee Resource Groups and leadership programs that celebrate every voice Achieve genuine work-life balance in a supportive R&D environment Pursue _Progress_. Discover _Extraordinary_. Join Sanofi and step into a new era of science - where your growth can be just as transformative as the work we do. We invest in you to reach further, think faster, and do what's never-been-done-before. You'll help push boundaries, challenge convention, and build smarter solutions that reach the communities we serve. Ready to chase the miracles of science and improve people's lives? Let's Pursue Progress and Discover Extraordinary - together. At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, protected veteran status or other characteristics protected by law. \LI-FRA \LI-Hybrid Pursue _progress_, discover _extraordinary_ Better is out there. Better medications, better outcomes, better science. But progress doesn't happen without people - people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let's be those people. At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity. Watch our ALL IN video (https://www.youtube.com/watch?v=SkpDBZ-CJKw&t=67s) and check out our Diversity Equity and Inclusion actions at sanofi.com (https://www.sanofi.com/en/our-responsibility/equality-and-inclusiveness) ! Global Terms & Conditions and Data Privacy Statement (https://www.sanofi.com/en/careers/global-terms-and-conditions/) Sanofi is dedicated to supporting people through their health challenges. We are a global biopharmaceutical company focused on human health. We prevent illness with vaccines, provide innovative treatments to fight pain and ease suffering. We stand by the few who suffer from rare diseases and the millions with long-term chronic conditions. With more than 100,000 people in 100 countries, Sanofi is transforming scientific innovation into healthcare solutions around the globe. Discover more about us visiting www.sanofi.com or via our movie We are Sanofi (https://youtu.be/96EwNjb1TLo) As an organization, we change the practice of medicine; reinvent the way we work; and enable people to be their best versions in career and life. We are constantly moving and growing, making sure our people grow with us. Our working environment helps us build a dynamic and inclusive workplace operating on trust and respect and allows employees to live the life they want to live. All in for Diversity, Equity and Inclusion at Sanofi - YouTube (http://www.youtube.com/watch?v=SkpDBZ-CJKw&t=2s)